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A spatial model of autophosphorylation of CaMKII in a glutamatergic spine suggests a network-driven kinetic mechanism for bistable changes in synaptic strength

Introduction

Provided here are the data and software described in the article entitled "A spatial model of autophosphorylation of CaMKII in a glutamatergic spine suggests a network-driven kinetic mechanism for bistable changes in synaptic strength", Posted on bioRxiv in 2024.

Downloads

MCell Model and Movie Files

The MOV file CaMKII_multiburst_color.mov contains the Supplemental movie file to accompany the article.

The PDF file CaMKII_multiburst_color_caption.pdf contains the caption explaining the movie file.

The gzipped tar file spatial_camkii_models.tar.gz contains the MCell model files described in the article.

There are four model files in the tar.gz file:

spine_camkii_model_cam_nontrapping_pp1_nonblocking.blend

spine_camkii_model_cam_nontrapping_pp1_blocking.blend

spine_camkii_model_cam_trapping_pp1_nonblocking.blend

spine_camkii_model_cam_trapping_pp1_blocking.blend